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Image Unavailable-BOSSBS-2763R-FITC

Anti-CRK Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: Crk p38 (CrkII) is an isoform of the protein Crk. CrkI and CrkII are produced from the same crk gene by alternative splicing. The two isoforms differ in their biological activities with CrkII having less transforming activity than CrkI.Crk p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers. In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth.
Référence Produit: BOSSBS-2763R-FITC
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6043R-A555

Anti-NBL1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: NBL1 (Neuroblastoma, suppression of tumorigenicity 1) is a candidate tumor suppressor of neuroblastoma and may play a role in preventing cells from entering the final stage (G1/S) of the transformation process. NBL1 is a member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. It is a member of a class of glycoproteins shown to be secreted inhibitors of the transforming growth factor-beta (TGF-beta) and bone morphogenic protein pathways.
Référence Produit: BOSSBS-6043R-A555
UOM: 1 * 100 µl
Fournisseur: Bioss
Product Image-BSENC-1541-100

Anti-TGF-1 Chicken Polyclonal Antibody

Description: Transforming growth factor beta-1 (TGFB1) is a multi-functional cytokine with roles in proliferation, differentiation and other functions in many cell types. The secreted TGFB1 protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide (Ref: SWISS-Prot).
Référence Produit: BSENC-1541-100
UOM: 1 * 100 µl
Fournisseur: Biosensis
Image Unavailable-BOSSBS-6165R-A350

Anti-HRAS Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.
Référence Produit: BOSSBS-6165R-A350
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6136R-CY5.5

Anti-AdV 5 E1A Rabbit Polyclonal Antibody (Cy5.5®)

Description: The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105.
Référence Produit: BOSSBS-6136R-CY5.5
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-AGLS240005

AdEasy Adenoviral vector systems

Description: The AdEasy system saves you a month of work over traditional methods by producing the recombinant adenoviral plasmid by homologous recombination in <i>E. coli</i>. The AdEasy XL system includes BJ5183 cells pre-transformed with the pAdEasy-1 plasmid, this feature dramatically decreases background caused by the non-recombinant shuttle plasmid.
Référence Produit: AGLS240005
UOM: 1 * 2,5 µG
Fournisseur: AGILENT
Image Unavailable-BOSSBS-4778R-A350

Anti-TNFRSF8 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Description: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (By similarity).
Référence Produit: BOSSBS-4778R-A350
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-4778R-A488

Anti-TNFRSF8 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (By similarity).
Référence Produit: BOSSBS-4778R-A488
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6817R-A488

Anti-MAGEA11 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: Acts as androgen receptor coregulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression.
Référence Produit: BOSSBS-6817R-A488
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6385R-A488

Anti-GAS1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
Référence Produit: BOSSBS-6385R-A488
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-6223R-CY5.5

Anti-BCAR1 Rabbit Polyclonal Antibody (Cy5.5®)

Description: BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion
Référence Produit: BOSSBS-6223R-CY5.5
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-13115R-A647

Anti-ETV6 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Description: Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation.
Référence Produit: BOSSBS-13115R-A647
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-4736R-CY5.5

Anti-HMMR Rabbit Polyclonal Antibody (Cy5.5®)

Description: Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity.
Référence Produit: BOSSBS-4736R-CY5.5
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-ICNA0215002901

Kanamycine sulfate ∼735 μg/mg (de Streptomyces kanamyceticus), poudre blanche

Description: Kanamycin Monosulfate is an aminoglycoside bacteriocidal antibiotic which acts as an inhibitor of protein biosynthesis by producing a misreading of the 70s-ribosome.
Kanamycin Monosulfate used in biotechnology applications to inhibit protein synthesis. It is also used as a selection agent for cells transformed with kanamycin B (neoR, kanR) resistance gene.
Mode of Action: Binds to 70S ribosomal subunit; inhibits translocation; elicits miscoding. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria, and mycoplasma.
Référence Produit: ICNA0215002901
UOM: 1 * 1 g
Fournisseur: MP Biomedicals

Certificats.


Image Unavailable-BOSSBS-4778R-CY5.5

Anti-TNFRSF8 Rabbit Polyclonal Antibody (Cy5.5®)

Description: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (By similarity).
Référence Produit: BOSSBS-4778R-CY5.5
UOM: 1 * 100 µl
Fournisseur: Bioss
Image Unavailable-BOSSBS-4778R-CY7

Anti-TNFRSF8 Rabbit Polyclonal Antibody (Cy7®)

Description: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (By similarity).
Référence Produit: BOSSBS-4778R-CY7
UOM: 1 * 100 µl
Fournisseur: Bioss
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