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Mycalolide B 98

Marques : ENZO LIFE SCIENCES
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Total Evaluation: 0
Moyenne des Notes : sur 5

BMLT1230020
ENZOBMLT1230020EA 394 EUR
ENZOBMLT1230020
Mycalolide B 98
Mycalolide B

Depolymerizes actin


Mycalolide B is a novel marine natural product which binds to actin in a 1:1 molar ratio (Kd=13-20 nM). It selectively and completely depolymerizes F-actin to G-actin via a mechanism distinct from that of the cytochalasins. Unlike cytochalasins, it inhibits actin-activated Mg2+-ATPase from rabbit skeletal muscle.


Isolated from the marine sponge Mycale sp.

Numéro CAS: 122752-21-0

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