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Anti-IGF1R Rabbit Polyclonal Antibody (Cy7®)

Fournisseur: Bioss
Ratings: Ecrire un avis

Total Evaluation: 0
Moyenne des Notes : sur 5

BS-0680R-CY7
BOSSBS-0680R-CY7EA 893 EUR
BOSSBS-0680R-CY7
Anti-IGF1R Rabbit Polyclonal Antibody (Cy7®)
Anticorps
When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinityEn savoir plus
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