Votre recherche pour: Fumonisin+B2

Référence Produit: (BOSSBS-5372R-A555)

Fournisseur: Bioss

Description: Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-5373R-A350)

Fournisseur: Bioss

Description: Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).

UOM: 1 * 100 µl

*Promo

Référence Produit: (ROCK200-302-N86)

Fournisseur: Rockland Immunochemicals

Description: Anti-CD45.2 is useful for immunochemistry, Immunoprecipitation, Immunofluorescence, and Flow Cytometry using mouse spleen cells, or an appropriate cell type (where indicated).

UOM: 1 * 500 µG

*Promo

Référence Produit: (BOSSBS-6656R-A680)

Fournisseur: Bioss

Description: Essential for the control of the cell cycle at the G2/M (mitosis) transition.

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-2571R-CY7)

Fournisseur: Bioss

Description: Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2.

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-2571R-CY3)

Fournisseur: Bioss

Description: Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2.

UOM: 1 * 100 µl

*Promo

Référence Produit: (ROCK200-326-I51)

Fournisseur: Rockland Immunochemicals

Description: Anti-AKT1 APC Antibody is suitable for Flow Cytometry, ELISA, immunochemistry, and western blotting. Expect a band approximately 56 kDa in size corresponding to AKT1 Protein by western blotting in the appropriate cell lysate or extract.

UOM: 1 * 50 µG

*Promo

Référence Produit: (BOSSBS-2571R-A488)

Fournisseur: Bioss

Description: Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2.

UOM: 1 * 100 µl

*Promo

Référence Produit: (ENZOBMLNK1040001)

Fournisseur: ENZO LIFE SCIENCES

Description: A potent and selective bradykinin B2 antagonist.

UOM: 1 * 1 mg

New Product *Promo

Référence Produit: (BOSSBS-2571R-HRP)

Fournisseur: Bioss

Description: Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2.

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-2571R-A750)

Fournisseur: Bioss

Description: Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2.

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-2571R-A555)

Fournisseur: Bioss

Description: Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2.

UOM: 1 * 100 µl

*Promo

Référence Produit: (BOSSBS-3913R-CY5.5)

Fournisseur: Bioss

Description: Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost.

UOM: 1 * 100 µl

*Promo

Référence Produit: (1566908.)

Fournisseur: USP

Description: USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.

UOM: 1 * 20 mg

*Promo

Référence Produit: (ENZOADI905787100)

Fournisseur: ENZO LIFE SCIENCES

Description: Bradykinin (BK) is a nine-amino acid peptide produced by kallikrein cleavage of kininogen precursor proteins in tissue and plasma, and is an important regulator of vascular and pain responses to tissue injury. Two receptors (B1 and B2) have been identified as mediators of BK signaling, and are both members of the seven-transmembrane domain-containing G-protein coupled receptor (GPCR) family. The B2 receptor is constitutively expressed in smooth muscle and neurons, whereas B1 expression is induced following tissue injury or during inflammation. The B2 receptor displays high affinity for BK and Lys-BK peptide agonists, while the B1 receptor displays highest affinity to des-Arg9-BK and des-Arg10-kallidin. Both receptors are best characterized as signaling via coupling to Gq alpha subunits (particularly Gq/11), leading to activation of phospholipase C beta, hydrolysis of PI, and an intracellular increase in free calcium, although coupling through Gi, Gs, and G12/13 has also been observed.

UOM: 1 * 100 µG

New Product *Promo

Référence Produit: (BOSSBS-3913R-A350)

Fournisseur: Bioss

Description: Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost.

UOM: 1 * 100 µl

*Promo